The main reason to store extracted stem cells is commercial. Due to the space required, whole cord blood is 9 times more expensive to store than extracted stem cells. The volume reduction methods were developed specifically to allow public banks to operate efficiently when considering treatments for leukaemia.
The commercial ‘space consideration’ issue was highlighted in a report entitled New trends in umbilical cord blood transplantation by bloodjournal.org. It comments that the majority of the world’s blood banks extract to save space costs. This is acceptable if only blood disorders are to be treated using the sample.
Extracted stem cells remove VSELs – importantly, VSELs, which are found in the same gradient density as red blood cells, are lost by centrifuge extraction of stem cells before storage are simply thrown away – as are key hormones and growth factors.